The following table provides information on supported and unsupported operating systems and platform targets for Optical Prime scans.
| Platform/OS | Run Collector Locally | Collect Remotely | Remotely Connect from OS |
| Windows | |||
| Windows 11 | YES | YES | YES |
| Windows 10 | YES | YES | YES |
| Windows 8.1 | YES | YES | YES |
| Windows 8 | YES | YES | YES |
| Windows 7 | YES | YES | YES |
| Windows Vista | NO | YES | YES |
| Windows Server 2022 | YES | YES | YES |
| Windows Server 2019 | YES | YES | YES |
| Windows Server 2016 | YES | YES | YES |
| Windows Server 2012 R2 | YES | YES | YES |
| Windows Server 2012 | YES | YES | YES |
| Windows Server 2008 | YES | YES | YES |
| Windows Server 2003 | NO | YES | YES |
| Hyper-V | YES | YES | YES |
| VMware vCenter 3.5+ with ESX Server 3.5+ | NO | YES | NO |
| Linux | |||
| Red Hat Enterprise Linux 7+ | YES | YES | YES |
| SuSE 10+ | YES | YES | YES |
| Ubuntu 11+ | YES | YES | YES |
| Gentoo 12+ | YES | YES | YES |
| CentOS 5+ | YES | YES | YES |
| Citrix Xen Server 6+ | YES | YES | NO |
| KVM | YES | YES | YES |
| Unsupported | |||
| Mac OS | |||
| Solaris | |||
| HP-UX | |||
| AIX | |||
| BSD |